reduction

2000s – Human Genome Project successfully maps human DNA

In June 2006 it was announced that the first working draft of the full human DNA sequence had been released by the Human Genome Project. In the years following researchers all over the world have used this resource to gain insight into a number of fields while reducing the need for animal testing. By studying […]

May 27th, 2014|Timeline, TL_Alternatives|Comments Off

1991 – LD50 test banned

The highly controversial Median Lethal Dose Test, or LD50, was developed by J. W. Trevan in 1927 as a means to determine characteristics in acute toxicity. However, due to the necessity to terminate large numbers of test subjects as a requisite of the test it received heavy criticism. In 1991 the UK Government decided upon […]

May 27th, 2014|Timeline, TL_legislation|Comments Off

1907 – Harrison grows from nerve cells by ‘hanging drop’ technique

The turn of the century witnessed an influx of cell culture in experimentation. However, few of the advancements made were as pivotal as the work conducted by Ross Granville Harrison at Johns Hopkins University in 1907. To this point, in vitro work had become quite good at observing organic tissue microscopically, however, attempts to manipulate […]

May 27th, 2014|Timeline, TL_Alternatives|Comments Off

FRAME’s new Director

FRAME has appointed a new Director to oversee its research programme at the Nottingham office. Dr Gerry Kenna is a drug safety scientist with extensive industrial safety assessment experience, including 11 years in the pharmaceutical industry. Prior to that he had a highly successful academic career. He is recognised nationally and internationally in the field […]

October 6th, 2014|Press, Rightbox|Comments Off

GM Mice

The use of genetically modified mice is increasing. This study is an investigation of the driving forces behind the rise in numbers of genetically modified (GM) mice in laboratories.  Study of trends in the use of GM mice and their efficacy as a model for human disease. Inquiry into the scope of the areas of research, the […]

June 26th, 2014|Research|Comments Off