cell culture

1978 – Synthetic production of human insulin

Prior to 1978, insulin for human use was purified from animal sources, commonly pigs or dogs. It was the work conducted by researchers at Genentech and City of Hope Medical Research Centre that would provide the progression away from the necessity for animals to produce insulin by successfully synthesising ‘human-insulin’. By editing the DNA of […]

May 27th, 2014|Timeline, TL_Alternatives|Comments Off

1907 – Harrison grows from nerve cells by ‘hanging drop’ technique

The turn of the century witnessed an influx of cell culture in experimentation. However, few of the advancements made were as pivotal as the work conducted by Ross Granville Harrison at Johns Hopkins University in 1907. To this point, in vitro work had become quite good at observing organic tissue microscopically, however, attempts to manipulate […]

May 27th, 2014|Timeline, TL_Alternatives|Comments Off

Developing pain relief drugs

Cell based models to help identify potential new analgesics. Research focussing on elucidating the key molecular mechanisms by which fatty acid metabolites or lipids signal to ion channel proteins involved in pain detection in sensory neurons, that is, the chemical pathways by which the body feels pain. The overall aim of the project is to […]

June 26th, 2014|Research|Comments Off