Statement from the FRAME Trustees: The catastrophic adverse effects reported last week in a clinical trial undertaken in France were unexpected and extremely surprising. One of six people treated with repeated doses of a new investigational drug in a Phase I clinical trial was initially left brain dead and then died, four others had severe […]
FRAME is concerned that health claims are being made about e-cigarettes without the benefit of accurate data. In the latest issue of FRAME’s scientific journal ATLA, Dr Robert Combes and Professor Michael Balls look at statements made by Public Health England (PHE) regarding the potential harm from e-cigarettes, compared with smoking tobacco products.
PHE has stated […]
Many people still seem unsure about the current situation regarding cosmetics testing in the UK. FRAME has received several inquiries from people who were given gifts at Christmas that had our logo on the packaging, and have asked if it meant the product was not tested on animals.
Since early 2013 it has been illegal to […]
The work of scientists and campaigners from around the world to end animal testing is being celebrated in a special issue of FRAME’s peer-reviewed journal ATLA (Alternatives to Laboratory Animals) Journal.
Produced each year in collaboration with the Lush Prize, the largest annual prize fund rewarding initiatives to end animal testing for toxicology research, the special […]
The Home Office has issued a progress report on what it is doing to reduce the use of animals in scientific research. The department set out plans in a document last February, which included three strategic priorities.
advance the use of the ThreeRs within the UK;
use international leadership to influence the uptake and adoption of […]
Commercially available artificial human skin models developed in the early 1990s provided an extremely useful alternative for researchers studying in vitro skin corrosion and irritation, as well as topical responses and phototoxicity. Prior to the development of models such as EpiSkin, EpiDerm, EST1000, and Living Skin Equivalent (LHE), in vivo tests on either human or animals subjects were […]
FRAME staff and Trustees, and post-graduates from the FRAME Alternatives Laboratory took part in the ninth World Congress on Alternatives and Animal Use in the Life Sciences, in Prague, Czech Republic.
Two posters featuring FRAME research were displayed. One was by FRAME Scientific Officer Kevin Coll, on the rise in use of genetically modified (GM) mice […]
FRAME does not give a definitive answer to this question because it is very subjective. Individual people draw the line between what is, and what is not, acceptable in different places.
Some people would choose not to take a headache tablet if many animals had been killed in its production, but the same people might take […]