Three Rs

2010 – European Union agrees on Directive 63/2010/EU

Europe-wide regulation of animals used for scientific purposes made a significant advancement with the adoption of Directive 63/2010/EU in September of 2010. The new directive improved on the previous one, Directive 86/609/EEC, by removing many of the discrepancies in protocols between European nations that often lead to quite obviously varying levels of protection for the […]

May 27th, 2014|Timeline, TL_legislation|Comments Off

1969 – FRAME founded

FRAME was founded and registered as a charity in 1969 by Dorothy Hegarty in Wimbledon, London. Since then, FRAME has moved to its current office in Nottingham in 1981 and established the FRAME Alternatives Laboratory at the University of Nottingham in 1991. The first issue of FRAME’s peer-reviewed international science journal Alternatives to Laboratory Animals (ALTA) […]

May 27th, 2014|Timeline, TL_Social|Comments Off

1959 – Russell and Burch publish The Principles

The Principles of Humane Experimental Technique written by W.M.S. Russell and R.L. Burch in 1959 is arguably the most influential moment in alternatives to the use of animals in experimentation history. Although it had little impact when it was first published, the book, and the concepts introduced by Russell and Burch, would prove to be exceptionally important […]

May 27th, 2014|Timeline, TL_Social|Comments Off

FRAME Annual Lecture 2014

The latest FRAME Annual Lecture was a huge success and sparked an in-depth debate on the future of drug development and testing.

Speaker Dr Malcolm Skingle, Director of Academic Liaison at Glaxo Smith Kline, discussed using innovation to promote the Three Rs. He outlined changes in the use of animals to test new drugs and demonstrated […]

October 17th, 2014|Press, Rightbox|Comments Off

FRAME’s new Director

FRAME has appointed a new Director to oversee its research programme at the Nottingham office. Dr Gerry Kenna is a drug safety scientist with extensive industrial safety assessment experience, including 11 years in the pharmaceutical industry. Prior to that he had a highly successful academic career. He is recognised nationally and internationally in the field […]

October 6th, 2014|Press, Rightbox|Comments Off

A ‘road map’ toward ending severe suffering of laboratory animals

The RSPCA has drawn up a plan that aims to end severe suffering for animals used in research and testing.  The road-map has been released in response to changes in EU and UK legislation and has been published in FRAME’s scientific journal ATLA.

Until now scientists have not been required to record how many test animals […]

September 30th, 2014|News, Press|Comments Off

Spreading the Three Rs message to China

An abridged version of the book that first set out the Three Rs principles of alternatives to animal experimentation has been translated into Chinese, and will be distributed to libraries and universities throughout China.

China has so far been slow to adopt alternatives – cosmetics testing on animals is still required by law there, for example […]

September 19th, 2014|News|Comments Off