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The Journal


Alternatives to Laboratory Animals - ATLA

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Papers List

List of papers, year 2005

Thomas, R.J., Bhandari, R., Barrett, D.A., Bennett, A.J., Fry, J.R., Powe, D., Thomson, B.J. and Shakesheff, K.M.   The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro.    Cells Tissues Organs, 181(2), 67-79 (2005)   [Abstract]   [Purchase from publisher]

Horgan, G. W.   Interpretation of two-stage experiments in animal studies.    Laboratory Animals, 39(1), 75-79 (2005)   [Abstract]   [Purchase from publisher]

Bhogal, N., Grindon, C. and Combes, R.   Revolutionising the Testing of Medicines and Chemicals in Europe.    AV Magazine, Spring 2005, 18-19.   [Abstract]   [AV Magazine]

Hudson, M.   The welfare and scientific advantages of non-invasive imaging of animals used in biomedical research.    Animal Welfare 14(4), 303-317 (2005).   [Abstract]   [Purchase from publisher]

Moore, P., Ogilvie, J., Horridge, E., Mellor, I.R. and Clothier, R.H.   The development of an innervated epithelial barrier model using a human corneal cell line and ND7/23 sensory neurons.    European Journal of Cell Biology, 84, 581-592 (2005).   [Abstract]   [Purchase from publisher]

Smith, D., Combes, R., Depelchin, O., Jacobson, S.D., Hack, R., Luft, J., Lammens, L., von Landenberg, F., Phillips, B., Pfister, R., Rabemampianina, Y., Sparrow, Stark, C. and Stephan-Gueldner, M.    Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.    Regulatory Toxicology and Pharmacology, 41, 95-101 (2005).   [Abstract]   [Purchase from publisher]

Grindon, C., Bhogal, N., Combes, R. and Balls, M.    The scientific, animal welfare and regulatory implications of the EU REACH system for chemical safety.    TOPRA Regulatory Rapporteur, 2(4), 16-22 (2005).   [Abstract]   [Purchase from publisher]

Combes, R.D.   Assessing risk to humans from chemical exposure by using non-animal test data.    Toxicology in Vitro, 19(7), 921-924 (2005).   [Abstract]   [Purchase from publisher]

Bhogal, N., Grindon, C., Combes, R. and Balls, M.   Toxicity testing: creating a revolution based on new technologies.    Trends in Biotechnology, 23(6), 299-307 (2005).   [Abstract]   [Purchase from publisher]

Balls, M. and Combes, R.   The need for a formal invalidation process for animal and non-animal tests.    ATLA, 33, 299-308 (2005).   [Abstract]    [PDF]

Balls, M. and Combes, R.   Validation at a crossroads.    ALTA, 33, 187 (2005).   [Abstract]    [PDF]

Balls, M.   The dependence of the happiness of superstar scientists on the freedom to conduct animal experiments.    ATLA, 33, 437-438 (2005).   [Abstract]    [PDF]

Balls, M.   The ethics of research involving animals: the report of the Nuffield Council on Bioethics, May 2005.    ATLA, 33, 649 (2005).   [Abstract]    [PDF]

Bhogal, N.   The EU REACH system: blessing in disguise or wolf in wolf’s clothing?    ATLA, 33, 81-82 (2005).   [Abstract]    [PDF]

Bhogal, N., Hudson, M., Balls, M. and Combes, R.D.   The use of non-human primates in biological and medical research: evidence submitted by FRAME to the Academy of Medical Sciences/Medical Research Council/Royal Society/Wellcome Trust Working Group.    ATLA, 33, 519-527 (2005).   [Abstract]    [PDF]

Combes, R. and Balls, M.   Intelligent testing strategies for chemicals testing — a case of more haste, less speed?    ATLA, 33, 289-297 (2005).   [Abstract]    [PDF]

Combes, R.   “Europe goes alternative” — what’s all the fuss about?    ATLA, 33, 459-552 (2005).   [Abstract]    [PDF]

Farzaneh, P., Allameh, A., Pratt, S., Moore, N., Travis, L., Gottschalg, E., Kind, C. and Fry, J.   Increased heat shock protein 70 expression following toxicant-mediated cytotoxicity: a ubiquitous marker of toxicant exposure?    ATLA, 33, 105-110 (2005).   [Abstract]    [PDF]

Grindon, C. and Bhogal, N.   The fourth EC report on the statistics of laboratory animal use: trends, recommendations and future prospects.    ATLA, 33, 417–426 (2005).   [Abstract]    [PDF]

Hudson, M., Bhogal, N. and Balls, M.   The use of non-human primates in regulatory toxicology: comments submitted by FRAME to the Home Office.    ATLA, 33, 529-540 (2005).   [Abstract]    [PDF]

Wilkinson, P.J. and Clothier, R.H.   Comparison of an animal product free medium and normal growth supplement on growth and barrier integrity of a human corneal epithelial cell line.    ATLA, 33(5), 509-518 (2005).   [Abstract]    [PDF]

Grindon, C.   The fourth EC report on laboratory animal use — is it sufficiently revealing?    ATLA, 33, 1-2 (2005).   [Abstract]    [PDF]

Combes, R. and Balls, M.   Opportunities for the Government to actively promote the three Rs during the UK’s presidency of the European Union (1 July to 31 December 2005).    ATLA, 33, 317–311 (2005).   [Abstract]    [PDF]