Past research projects
FRAME studies demand for animals in the development and safety testing of a wide range of substances and how the Three Rs can be applied to reduce, refine or replace animal use.
- Food additives testing
- Testing complex mixtures and nanoparticles without using animals
Use of sentient animals
A series of projects focus on how different species and strains of animals are used for medical and biomedical research that look at the relevance and animal welfare consequences of these studies.
- Primates in research and testing
- Cats in neurobiological research
There have been many important developments in several fields of research that have resulted in methods that have so far had limited application in terms of reducing, refining and replacing animal studies. FRAME is currently looking at how these developments can be made more widely available and used to implement the Three Rs.
Humans as alternatives to animals
Species differences often confound the extrapolation of information from animal studies to humans as a way of predicting human safety and efficacy. Studies on human cells, tissues and volunteers are generally more relevant. FRAME has a number of projects that look at: