Projects timeline

2010

European Partnership for Alternative Approaches to Animal Testing (EPAA) poster award at annual conference. Reduction and Refinement: Combining Excellence in Science and Animal Welfare. Brussels.

Training School in the Experimental Design and Statistical Analysis of Biomedical Experiments

Committee members taught on the Manchester University reduction training course.

2009

Strategic Planning Chart for Reducing Animal Use in Biomedical Science 

Training School in the Experimental Design and Statistical Analysis of Biomedical Experiments

Poster at 7th World Congress on Alternatives & Animal Use in the Life Sciences. Rome.

Special Edition of Alternatives to Laboratory Animals. (ATLA) Reduction.

2008

Training School in the Experimental Design and Statistical Analysis of Biomedical Experiments

2007

NC3Rs Stakeholder Meeting on Experimental Design, UK

An interactive session on experimental design.

2006

Response to the online Nature Peer Review Debate, Quality and Value: Statistics in peer review by David Ozonoff

A letter was submitted on behalf of the FRSC to the Nature online blog, detailing the importance of strategic planning and good experimental design. This was published in June and can still be viewed here.

2006

FRAME Focus on Reduction Leaflet

This leaflet is aimed at introducing the concept of reduction to students and school children. It includes worked examples of how a reduction in the number of animals needed in experiments can be achieved through good experimental design and appropriate statistical analysis.

2003

British Pharmacological Society's Winter Meeting

Various members of the Committee gave presentations and were involved in running a workshop on Reduction.

2001-2004

Joint LASA/FRSC meeting ‘Scientists, Statisticians, Ethical Review Process (ERP Members and Trainers: Optimising Animal Use by Enhanced Teamwork’ [April 2001]

FRSC symposium ‘Reduction – Current Status and Future Prospects’ [October 2002]

The first of these two meetings was aimed at investigating how various parties could work together to achieve reduction, in particular to focus on ways of improving the consultation process between scientists and statisticians.

The second meeting was organised to enable invited speakers to review progress in Reduction and to identify where further development was needed.  It included a forum to discuss ‘Where do we go now?’ The proceedings from these two meetings were published collectively in an ATLA supplement in 2004.

ATLA 32(Suppl. 2), (2004)

2001

Workshop on Improving the Design of Animal Experiments and Reducing Animal Use, AALAS Meeting, USA

Various members were involved in running this workshop.

2001

Experimental Design CD

This CD-ROM was aimed at teaching scientists better experimental design and was developed in association with Dr David Dewhurst (Director of Learning Technology, University of Edinburgh). Essential aspects such as, how to define hypotheses, how to identify appropriate animal models and how to identify the fundamental units are covered.  

   
1999

Guidelines for Editors

A brief set of guidelines to encourage journal editors to include a statement concerning the importance of the Three Rs in their journal.  This was developed in association with Professor Bert van Zuptphen (University of Utrecht) and circulated to more than 100 journals.  Several journals have either printed it or referred authors to the FRAME website.