What FRAME does
FRAME's main aim is to find scientific methods that remove the need for animals in laboratories. They can be alternative research and testing methods such as cells in culture, computer-based approaches, the use of donated human cells and tissues, or studies on volunteers.
We look at ways to reduce the number of animals involved in experiments and how to refine systems to minimise the distress and pain that test animals undergo.
FRAME supports laboratory research at the University of Nottingham, and some grants have been awarded to other scientists working on the development of non-animal methods.
FRAME scientists carry out desk-based research into a range of areas and investigate how to implement the Three Rs.
We also campaign in a number of areas and lobby for changes in legislation, where appropriate.
At FRAME we analyse UK annual statistics and EU statistics on laboratory animal use to identify areas where Three Rs initiatives can be better applied. FRAME is concerned that animal experiments are persistently rising each year, largely due to the continuing use of genetically modified mice and an increased interest in investigations and tests in fish.
FRAME trains working animal scientists in methods that help them to use fewer animals and to extract more and better data from their experiments without the need to use more animals.