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Alternatives to Laboratory Animals - ATLA

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Human Alternatives to Animal Studies

Human Alternatives to Animal Studies brought together academics and pharmaceutical industry scientists to discuss how human cells and tissues can be ethically acquired and used in fundamental research and the development of new medicines and other therapies.

shervanthiKeynote speaker Shervanthi Homer-Vanniasinkam, Consultant Vascular Surgeon at The General Infirmary, Leeds, opened the proceedings with a talk entitled The Quest for Alternative Preclinical Testing Modalities: a Clinician-Scientist's Perspective.





The conference featured many interesting speakers who gave excellent presentations and no doubt inspired a great deal of discussion about how human cells can be ethically acquired and used in research in the future.


FRAME was pleased to host an event where speakers from so many different sections of research and industry had the opportunity to exchange ideas. Much new light was shed on the innovative and exciting work being undertaken throughout the UK to discover new, valid methods that do not require the use of animals.


FRAME Scientific Director Dr Nirmala Bhogal said: “Using human volunteers and donated tissues takes the guesswork out of extrapolating animal data to humans and makes tests more relevant to human health and safety. Human alternatives can represent patient populations or particular subsets of the population more effectively.


 "They can also help to develop clinical management strategies and assist with designing
and interpreting the results from clinical trials. Last but not least, using human alternatives helps to phase out the use of animals in medical research and may reduce healthcare costs because fewer drugs will fail late in the development pipeline. That is why we have chosen this as the theme of our symposium.”


The event took place at the University of Nottingham Jubilee Campus. Topics covered included human tissue engineering, computer-based studies, clinical studies, human cell-based studies and organotypic models based on human cells and tissues.  The event featured established speakers as well as offering new researchers the opportunity to present their work.


Other speakers included: Guru Aithal – Consultant Hepatobiliary Physician, Queen’s Medical Centre, Nottingham, Dorothy Auer – School of Medical and Surgical Sciences, University of Nottingham, Robert Barber – Professor and Research Officer, Daresbury Laboratory, Kelly BéruBé – Director, Lung and Particle Research Group, Cardiff University, Andy Bennett – Director, FRAME Alternatives Laboratory, Nottingham, David Bunton – Co-founder and Chief Operating Officer, Biopta, Richard Grundy – Paediatric Neuro-oncology & Cancer Biology, University of Nottingham, Tim Hardingham – Wellcome Trust Centre for Cell-matrix Research, University of Manchester, Arun Holden – Professor of Computational Biology, University of Leeds, Mark Seymour – Chief Study Director, Xceleron Ltd, Paul Genever - University of York, and Phil Stephens – Head of Tissue Engineering and Reparative Dentistry, Cardiff University.


Archived september 21