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US Department of Agriculture seeking comments on humane endpoints

white miceThe U.S. Department of Agriculture (USDA) Center for Veterinary Biologics (CVB) regularly seeks public comment on drafts of proposed guidance documents concerning all aspects of veterinary vaccines production, testing, and distribution. Draft Notice 465 provides proposed guidance on the use of humane endpoints and methods in animal testing of biological products.


The draft document includes specific guidance regarding the use of humane endpoints in biological products testing, including guidance on humane endpoints for the rabies challenge test. The draft guidance also strongly encourages the use of anesthesia for intracerebral inoculation of mice during rabies vaccine testing.


More details can be found on the USDA website. (Opens in a new window)