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Alternatives to Laboratory Animals - ATLA

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FAL working on human liver model

Lab computerColorectal cancer often spreads to the liver and patients have to undergo surgery to remove part of the organ. One treatment, using oxaliplatin, sometimes causes fat deposition in the liver (steatosis), reducing its ability to recover from the surgery.

The FAL (FRAME Alternatives Laboratory) is trying to increase knowledge of how the treatment causes the steatosis by using human cell cultures to mimic different parts of the liver.

Click here to read an interview with FAL Director Dr Andrew Bennett about the project.

 Archived 13 May 2011