More collaboration needed in the hunt for new drugs

FRAME is calling for more collaboration between alternatives organisations, government and the pharmaceutical industry following publication of a new investigation of preclinical drugs  trials using laboratory animals.

Scientific papers covering more than 2,300 substances tested on rats, mice and rabbits were analysed to measure the likelihood ratio that chemicals showing no […]

The FRAME Alternatives Timeline

The use of animals in experiments is well documented. Its history and evolution can be traced through to contemporary techniques. Centuries ago, the ancient Greeks and Romans first began exploratory surgery on animals to discover the inner workings of living things. However, until now there has never been a […]

Increasing use of genetically modified mice

There has been an overall decrease in the total number of animals used for scientific procedures in the past 40 years. However, there has been a consistent increase in the breeding and use of genetically modified animals, mostly mice, over the same period.

Genetically modified mice (GMM) have become a […]