FRAME planning poster now in Portuguese

In response to requests by scientists in Portugal, FRAME has had one of its key documents translated into Portuguese. The Strategic Planning Flowchart helps researchers design experiments that use fewer animals and extract more information from […]

FRAME Debate video now online

“Total animal replacement in human medicine is a realistic goal but it’s a difficult challenge and it’s going to be a long-term goal.”
That was one of the conclusions of a debate held by FRAME at […]

FRAME response to mouse head transplant reports

FRAME has responded to recent press stories of mouse head transplants being carried out in China. The Wall Street Journal has reported that surgeon Professor Xiaoping Ren has carried out procedures on more than 1,000 mice, and […]

Students drink coffee to replace animal tests

A university in the United Arab Emirates has introduced a human-based experiment as a way of replacing animal models of the effects of drugs on body organs. Medical students now dose themselves with coffee to […]

FRAME response to EU “Stop Vivisection” initiative

The discussion this week of the “Stop Vivisection” initiative has highlighted several extremely important issues.

Firstly, the high priority that needs to be given to replacement of animal experiments with scientifically valid alternatives.
Secondly, the limited relevance […]

What will drive the end of animal testing?

In spite of campaigns by many bodies and individuals for an end to animal experimentation the numbers used in procedures in UK laboratories continue to rise. If a change is to happen there must be […]

Animal-free challenge for young researchers

Young scientists who wish to go into a career without ever being expected to use animals need to be determined, resourceful and tenacious. That is the conclusion of new research published in FRAME’s  online discussion […]

Education outreach – Cardiff

As part of its education outreach, FRAME takes part each year in a lecture session at the University of Cardiff. Students from the undergraduate biomedical class hear from various bodies concerned with animal use and […]

2015 Björn Ekwall Award

FRAME Life President and editor of its journal ATLA, Professor Michael Balls, has been chosen to receive the 2015 Björn Ekwall Memorial Award.

The Award honours the memory of Swedish researcher Björn Ekwall (pictured) by recognising […]

New FRAME Training School date announced

When scientists carry out experiments it is vitally important they are well designed, otherwise they may waste resources or give the wrong answers. This is especially serious when animals are used.

Good planning and design can […]

FRAME Annual Lecture 2014

The latest FRAME Annual Lecture was a huge success and sparked an in-depth debate on the future of drug development and testing.

Speaker Dr Malcolm Skingle, Director of Academic Liaison at Glaxo Smith Kline, discussed using […]

A ‘road map’ toward ending severe suffering of laboratory animals

The RSPCA has drawn up a plan that aims to end severe suffering for animals used in research and testing.  The road-map has been released in response to changes in EU and UK legislation and […]

Spreading the Three Rs message to China

An abridged version of the book that first set out the Three Rs principles of alternatives to animal experimentation has been translated into Chinese, and will be distributed to libraries and universities throughout China.

China has […]

FRAME attends Prague World Congress

FRAME staff and Trustees, and post-graduates from the FRAME Alternatives Laboratory took part in the ninth World Congress on Alternatives and Animal Use in the Life Sciences, in Prague, Czech Republic.

Two posters featuring FRAME research […]

More collaboration needed in the hunt for new drugs

FRAME is calling for more collaboration between alternatives organisations, government and the pharmaceutical industry following publication of a new investigation of preclinical drugs  trials using laboratory animals.

Scientific papers covering more than 2,300 substances tested on rats, […]

Home Office statistics on lab animal use released

A further increase in the use of genetically altered (GA) animals in laboratories flouts EU regulations and is in direct opposition to the UK Government’s pledge to reduce the numbers involved.  If the Government is going […]

The FRAME Alternatives Timeline

The use of animals in experiments is well documented. Its history and evolution can be traced through to contemporary techniques. Centuries ago, the ancient Greeks and Romans first began exploratory surgery on animals to discover […]

Locating the Middle Ground

A ‘middle ground’ exists, where the advocates and the opponents of vivisection can usefully negotiate, but where exactly is it? Discussions on the use of animals in scientific and medical experiments often attract extreme points […]

Increasing use of genetically modified mice

There has been an overall decrease in the total number of animals used for scientific procedures in the past 40 years. However, there has been a consistent increase in the breeding and use of genetically […]