The first FRAME debate was a huge success. It brought together experts from across the fields of industry, academia, politics, animal welfare and science promotion to discuss the proposition: Total animal replacement in human medicine is a realistic goal.
The speakers were: Dr Brian Burlinson, VP Safety Assessment and Principal Scientist at Huntingdon Life Sciences; Dr […]
FRAME is holding its first ever debate tomorrow (April 23) in London, on what can be done to bring an end to animal experiments more quickly. Experts from across the fields of industry, academia, politics, animal welfare and science promotion will get together to discuss the current status of alternatives to animal testing.
The debate aims […]
The Home Office has issued a progress report on what it is doing to reduce the use of animals in scientific research. The department set out plans in a document last February, which included three strategic priorities.
advance the use of the ThreeRs within the UK;
use international leadership to influence the uptake and adoption of […]
The Home Office is to introduce a ban on testing household products on animals with effect from October. The move follows a detailed consultation about the impact such a ban would have on industry and the economy.
The ban will apply to products bought by the public for use at home and in the […]
Researchers have announced that it might be possible to transplant a human head onto a donor body within two years – but FRAME is concerned about the ethical and scientific questions surrounding the project.
FRAME Scientific Director Dr Gerry Kenna said: “At first glance, the proposal to transplant a human head to a different body has […]
FRAME Life President and editor of its journal ATLA, Professor Michael Balls, has been chosen to receive the 2015 Björn Ekwall Memorial Award.
The Award honours the memory of Swedish researcher Björn Ekwall (pictured) by recognising scientists who have substantially contributed to the field of animal-free safety testing , for example by developing new in vitro […]
Among the keynote speakers at the International Conference of Alternatives to Animal Experimentation in Portugal in May will be independent drug development consultant Dr Robert Coleman whose talk will be : Humanising drug safety testing: a pragmatic validation study.
Dr Coleman published a paper in the latest issue of FRAME’s scientific journal ATLA (Alternatives to Laboratory […]
FRAME is calling for increased investment in cell-based and computer methods of drug testing following new research that demonstrates serious flaws in an animal model.
Cynomolgus monkeys are considered a valuable species for drug testing because of their size and their relatively close genetic parallels with humans. Now new experiments to investigate how the liver handles […]
Cynomolgus monkeys are resistant to drug induced liver injury caused by paracetamol
by Dr Gerry Kenna
FRAME Scientific Director
Prior to their registration for use in humans, all new drugs are subjected to a large battery of safety studies. These include an extensive series of investigations in experimental animals, which are undertaken in compliance with well-established regulatory guidelines, […]
The latest FRAME Annual Lecture was a huge success and sparked an in-depth debate on the future of drug development and testing.
Speaker Dr Malcolm Skingle, Director of Academic Liaison at Glaxo Smith Kline, discussed using innovation to promote the Three Rs. He outlined changes in the use of animals to test new drugs and demonstrated […]