News

News stories.

New research casts doubt on monkeys as drug testing model

FRAME is calling for increased investment in cell-based and computer methods of drug testing following new research that demonstrates serious flaws in an animal model.

Cynomolgus monkeys are considered a valuable species for drug testing because of their size and their relatively close genetic parallels with humans. Now new experiments to investigate how the liver handles […]

October 30th, 2014|News, Press|Comments Off

A ‘road map’ toward ending severe suffering of laboratory animals

The RSPCA has drawn up a plan that aims to end severe suffering for animals used in research and testing.  The road-map has been released in response to changes in EU and UK legislation and has been published in FRAME’s scientific journal ATLA.

Until now scientists have not been required to record how many test animals […]

September 30th, 2014|News, Press|Comments Off

Spreading the Three Rs message to China

An abridged version of the book that first set out the Three Rs principles of alternatives to animal experimentation has been translated into Chinese, and will be distributed to libraries and universities throughout China.

China has so far been slow to adopt alternatives – cosmetics testing on animals is still required by law there, for example […]

September 19th, 2014|News|Comments Off

FRAME attends Prague World Congress

FRAME staff and Trustees, and post-graduates from the FRAME Alternatives Laboratory took part in the ninth World Congress on Alternatives and Animal Use in the Life Sciences, in Prague, Czech Republic.

Two posters featuring FRAME research were displayed. One was by FRAME Scientific Officer Kevin Coll, on the rise in use of genetically modified (GM) mice […]

September 3rd, 2014|News|Comments Off

More collaboration needed in the hunt for new drugs

FRAME is calling for more collaboration between alternatives organisations, government and the pharmaceutical industry following publication of a new investigation of preclinical drugs  trials using laboratory animals.

Scientific papers covering more than 2,300 substances tested on rats, mice and rabbits were analysed to measure the likelihood ratio that chemicals showing no adverse reactions would behave the same […]

July 25th, 2014|News, Press|Comments Off

Home Office statistics on lab animal use released

A further increase in the use of genetically altered (GA) animals in laboratories flouts EU regulations and is in direct opposition to the UK Government’s pledge to reduce the numbers involved.  If the Government is going to keep its promise it needs to address this question urgently in order to stop the upward trend.

FRAME is deeply […]

July 10th, 2014|News, Press|Comments Off

The FRAME Alternatives Timeline

The use of animals in experiments is well documented. Its history and evolution can be traced through to contemporary techniques. Centuries ago, the ancient Greeks and Romans first began exploratory surgery on animals to discover the inner workings of living things. However, until now there has never been a simple way to track the developments […]

May 16th, 2014|News|Comments Off

Locating the Middle Ground

A ‘middle ground’ exists, where the advocates and the opponents of vivisection can usefully negotiate, but where exactly is it? Discussions on the use of animals in scientific and medical experiments often attract extreme points of view where two opposing sides appear to be intractable and no possibility of compromise exists. But there are many […]

May 27th, 2014|News, Press|Comments Off

Increasing use of genetically modified mice

There has been an overall decrease in the total number of animals used for scientific procedures in the past 40 years. However, there has been a consistent increase in the breeding and use of genetically modified animals, mostly mice, over the same period.

Genetically modified mice (GMM) have become a routine model for researchers in a […]

May 16th, 2014|News|Comments Off