anne

/Anne Jeffery

About Anne Jeffery

Anne Jeffery is FRAME's Communications Manager.

New skin model

It is well known that lipids (fatty substances) can have a positive effect on skin. A new project at the FRAME laboratory will enable close investigation of how lipids are absorbed to create those effects. The project will involve building three-dimensional models from keratinocytes, fibroblasts, melanocytes and immune cells. They will be isolated directly from [...]

February 27th, 2015|Research|Comments Off on New skin model

2015 Björn Ekwall Award

FRAME Life President and editor of its journal ATLA, Professor Michael Balls, has been chosen to receive the 2015 Björn Ekwall Memorial Award. The Award honours the memory of Swedish researcher Björn Ekwall (pictured) by recognising scientists who have substantially contributed to the field of animal-free safety testing , for example by developing new in [...]

February 25th, 2015|News, Press|Comments Off on 2015 Björn Ekwall Award

Towards a single R: Replacement

Among the keynote speakers at the International Conference of Alternatives to Animal Experimentation in Portugal in May will be independent drug development consultant Dr Robert Coleman whose talk will be : Humanising drug safety testing: a pragmatic validation study. Dr Coleman published a paper in the latest issue of FRAME’s scientific journal ATLA (Alternatives to [...]

February 5th, 2015|Press, Rightbox|Comments Off on Towards a single R: Replacement

New FRAME Training School date announced

When scientists carry out experiments it is vitally important they are well designed, otherwise they may waste resources or give the wrong answers. This is especially serious when animals are used. Good planning and design can have a major impact on reducing animal usage in research programmes and the the welfare of the animals used. [...]

January 21st, 2015|News|Comments Off on New FRAME Training School date announced

1994 Visible Human Project

The Visible Human Project is a collection of medical images which together offer a detailed, three-dimensional representation of normal male and female human bodies. It was created using two donated cadavers that have been preserved, scanned and sectioned, then recorded using transverse CT, MR and cryosection images. It has been carried out by the US [...]

December 5th, 2014|Timeline|Comments Off on 1994 Visible Human Project

1747 – First controlled medical trial

Scottish surgeon's mate James Lind carried out the first controlled medical trial by testing members of the UK Royal Navy in a bid to identify the cause of scurvy. He chose 12 sailors who were already suffering from the disease and provided an identical diet and accommodation in order to eliminate factors associated with those [...]

December 3rd, 2014|Timeline|Comments Off on 1747 – First controlled medical trial

1951 – HeLa cells

In 1951, the first human immortal cell line, HeLa, was established and successfully grown in vitro (1). The cells had been isolated from the cervical cancer of a patient called Henrietta Lacks. Up until that point, cells could be maintained in in vitro culture only temporarily. An immortal cell line allowed scientists to perform experiments [...]

November 28th, 2014|Timeline|Comments Off on 1951 – HeLa cells

Cynomolgus monkeys and paracetamol: background paper

Cynomolgus monkeys are resistant to drug induced liver injury caused by paracetamol by Dr Gerry Kenna Prior to their registration for use in humans, all new drugs are subjected to a large battery of safety studies. These include an extensive series of investigations in experimental animals, which are undertaken in compliance with well-established regulatory guidelines, [...]

October 30th, 2014|Background, Press, Rightbox|Comments Off on Cynomolgus monkeys and paracetamol: background paper

New research casts doubt on monkeys as drug testing model

FRAME is calling for increased investment in cell-based and computer methods of drug testing following new research that demonstrates serious flaws in an animal model. Cynomolgus monkeys are considered a valuable species for drug testing because of their size and their relatively close genetic parallels with humans. Now new experiments to investigate how the liver [...]

October 30th, 2014|Press, Rightbox|Comments Off on New research casts doubt on monkeys as drug testing model

FRAME Annual Lecture 2014

The latest FRAME Annual Lecture was a huge success and sparked an in-depth debate on the future of drug development and testing. Speaker Dr Malcolm Skingle, Director of Academic Liaison at Glaxo Smith Kline, discussed using innovation to promote the Three Rs. He outlined changes in the use of animals to test new drugs and [...]

October 17th, 2014|News, Press, Rightbox|Comments Off on FRAME Annual Lecture 2014