17 July 2015 The EU Reference Laboratory for Alternatives to Animal Testing (EURL Ecvam), part of the Commission's Joint Research Centre, has just published a strategy calling for more integration of non-animal methods into testing. The strategy aims at reducing animal testing while improving the protection of human health from exposure to chemicals. More information at [...]
15 July 2015 South Korea has recently issued threshold limits for a range of biocides. Its Ministry of Environment (MoE) has published a list of product safety and labelling standards for disinfectants, insect repellents and preservatives. A Priority Existing Chemicals (PEC) list was published on 1 July detailing 510 substances that must be registered before [...]
14 July 2015 Times Higher Education takes a look at how public engagement affects academic careers in the UK and US and finds worrying trends on both sides of the Atlantic. More here.
The FRAME Alternatives Lab is able to differentiate human mononuclear blood cells into human osteoclasts (bone eating cells). Osteoclast dysfunction has been observed in a variety of bone diseases including osteoarthritis. The lab is currently investigating potential therapeutic agents which will decrease osteoclast activity in arthritis and reduce bone and joint damage.
10 July 2015. Faster routes to new drugs. Using computers to speed up the drug discovery process. More at New Scientist.
Throughout its almost 50 year history FRAME's researchers have authored very many scientific papers in both its own journal and others. They have also submitted articles to publications aimed at lay people, in order to promote the Three Rs to educators and the general public. In addition they have written or translated a number of [...]
8 July 2015. Stanford Cardiovascular Institute (SCVI) at Stanford University is offering researchers access to their growing collection of iPS cell lines as well as creating iPS cells from samples sent to them. More at Stanford Website.
Much of the research into obesity and diabetes is carried out using transgenic animal models. FRAME's experience and that of many others is that such animal models are of little use when trying to study human diseases and responses to potential therapies. The FRAME Alternatives Laboratory cultures primary human adipocytes and skeletal muscle myotubes to [...]
In response to requests by scientists in Portugal, FRAME has had one of its key documents translated into Portuguese. The Strategic Planning Flowchart helps researchers design experiments that use fewer animals and extract more information from the work they carry out. When scientists perform experiments it is vitally important they are well designed. This is especially serious [...]
6 July 2015. The NHS has announced plans to trial artificial blood on patients by 2017 - the first such clinical trials in the world. More information at The New Scientist.