anne

About Anne Jeffery

Anne Jeffery is FRAME's Communications Manager.

1993 – First World Congress

The first World Congress on Alternatives & Animal Use in the Life Sciences was held in Baltimore, Maryland, sponsored by CAAT (The Johns Hopkins University Center for Alternatives to Animal Testing) It remains the primary international scientific conference series dedicated to the 3Rs.

Further Congress meetings were held approximately every two years in  Utrecht, Netherlands;  Rome, Italy; […]

June 19th, 2014|Timeline, TL_Social|Comments Off

1986 – EU Directive 86/609

EU Directive 86/609 for the protection of animals used for experimentation and other scientific purposes introduced. It included the rule : “An experiment shall not be performed if another scientifically satisfactory method of obtaining the result sought, not entailing the use of an animal, is reasonably and practicably available”.

June 19th, 2014|Timeline, TL_legislation|Comments Off

1981 – CAAT founded

In 1981 the Johns Hopkins University in Baltimore, Maryland founded its Center for Alternatives to Animal Testing (CAAT) as part of the University Bloomberg School of Public Health. Its aim is to promote humane science by supporting the creation, development, validation, and use of alternatives to animals in research, product safety testing, and education. We […]

June 19th, 2014|Timeline, TL_Social|Comments Off

More collaboration needed in the hunt for new drugs

FRAME is calling for more collaboration between alternatives organisations, government and the pharmaceutical industry following publication of a new investigation of preclinical drugs  trials using laboratory animals.

Scientific papers covering more than 2,300 substances tested on rats, mice and rabbits were analysed to measure the likelihood ratio that chemicals showing no adverse reactions would behave the […]

July 25th, 2014|News|Comments Off

Human Patient, Volunteer and Tissue Studies

As well as working with human cells, where possible the FRAME Alternatives Laboratory works with human patients and volunteers to increase understanding of human disease. Quite obviously, data obtained from human subjects is infinitely more relevant than data from animal models.
Dietary studies in overweight and obese humans
In conjunction with Clinicians and Physiologists at Nottingham University, we […]

August 6th, 2014|Research, Rightbox|Comments Off

FRAME essay competition winner

FRAME’s recent essay competition “What are the alternatives to using animals in laboratories?” attracted some strong entries. The winner, who received a £300 prize, was 17-year-old Emma Bryan, a student at  Cheltenham Ladies College.

Emma’s response to her success: “I am extremely happy to have taken part as I really enjoyed writing the essay and […]

July 21st, 2014|Rightbox|Comments Off

Home Office statistics on lab animal use released

A further increase in the use of genetically altered (GA) animals in laboratories flouts EU regulations and is in direct opposition to the UK Government’s pledge to reduce the numbers involved.  If the Government is going to keep its promise it needs to address this question urgently in order to stop the upward trend.

FRAME is […]

July 10th, 2014|News, Press|Comments Off

Development of a dynamic 3D model of liver for chronic toxicity testing

Technological advancements that provide the opportunity to develop better and more reliable models are essential to translational research.  At the FRAME Alternatives Laboratory at the University of Nottingham, PhD candidate Richard Maclennan has been working with the Zyoxel LiverChip device to determine its applicability and limitations for chronic toxicity testing.  The LiverChip recreates the […]

July 1st, 2014|Research, Rightbox|Comments Off

GM Mice

The use of genetically modified mice is increasing. This study is an investigation of the driving forces behind the rise in numbers of genetically modified (GM) mice in laboratories.  Study of trends in the use of GM mice and their efficacy as a model for human disease. Inquiry into the scope of the areas of research, […]

June 26th, 2014|Research|Comments Off

Developing pain relief drugs

Cell based models to help identify potential new analgesics. Research focussing on elucidating the key molecular mechanisms by which fatty acid metabolites or lipids signal to ion channel proteins involved in pain detection in sensory neurons, that is, the chemical pathways by which the body feels pain. The overall aim of the project is […]

June 26th, 2014|Research|Comments Off