anne

About Anne Jeffery

Anne Jeffery is FRAME's Communications Manager.

1994 Visible Human Project

The Visible Human Project is a collection of medical images which together offer a detailed, three-dimensional representation of normal male and female human bodies. It was created using two donated cadavers that have been preserved, scanned and sectioned, then recorded using transverse CT, MR and cryosection images.

It has been carried out by the US National […]

December 5th, 2014|Timeline|Comments Off

1993 – First World Congress

The first World Congress on Alternatives & Animal Use in the Life Sciences was held in Baltimore, Maryland, sponsored by CAAT (The Johns Hopkins University Center for Alternatives to Animal Testing) It remains the primary international scientific conference series dedicated to the 3Rs.

Further Congress meetings were held approximately every two years in  Utrecht, Netherlands;  Rome, Italy; Berlin, […]

June 19th, 2014|Timeline, TL_Social|Comments Off

1986 – EU Directive 86/609

EU Directive 86/609 for the protection of animals used for experimentation and other scientific purposes introduced. It included the rule : “An experiment shall not be performed if another scientifically satisfactory method of obtaining the result sought, not entailing the use of an animal, is reasonably and practicably available”.

June 19th, 2014|Timeline, TL_legislation|Comments Off

1981 – CAAT founded

In 1981 the Johns Hopkins University in Baltimore, Maryland founded its Center for Alternatives to Animal Testing (CAAT) as part of the University Bloomberg School of Public Health. Its aim is to promote humane science by supporting the creation, development, validation, and use of alternatives to animals in research, product safety testing, and education. We seek […]

June 19th, 2014|Timeline, TL_Social|Comments Off

1951 – HeLa cells

In 1951, the first human immortal cell line, HeLa, was established and successfully grown in vitro (1). The cells had been isolated from the cervical cancer of a patient called Henrietta Lacks. Up until that point, cells could be maintained in in vitro culture only temporarily. An immortal cell line allowed scientists to perform experiments […]

November 28th, 2014|Timeline|Comments Off

1747 – First controlled medical trial

Scottish surgeon’s mate James Lind carried out the first controlled medical trial by testing members of the UK Royal Navy in a bid to identify the cause of scurvy.

He chose 12 sailors who were already suffering from the disease and provided an identical diet and accommodation in order to eliminate factors associated with those influences. […]

December 3rd, 2014|Timeline|Comments Off

New research casts doubt on monkeys as drug testing model

FRAME is calling for increased investment in cell-based and computer methods of drug testing following new research that demonstrates serious flaws in an animal model.

Cynomolgus monkeys are considered a valuable species for drug testing because of their size and their relatively close genetic parallels with humans. Now new experiments to investigate how the liver handles […]

October 30th, 2014|News, Press|Comments Off

Cynomolgus monkeys and paracetamol: background paper

Cynomolgus monkeys are resistant to drug induced liver injury caused by paracetamol
by Dr Gerry Kenna
FRAME  Scientific Director

Prior to their registration for use in humans, all new drugs are subjected to a large battery of safety studies. These include an extensive series of investigations in experimental animals, which are undertaken in compliance with well-established regulatory guidelines, […]

October 30th, 2014|Background, Press, Rightbox|Comments Off

FRAME Annual Lecture 2014

The latest FRAME Annual Lecture was a huge success and sparked an in-depth debate on the future of drug development and testing.

Speaker Dr Malcolm Skingle, Director of Academic Liaison at Glaxo Smith Kline, discussed using innovation to promote the Three Rs. He outlined changes in the use of animals to test new drugs and demonstrated […]

October 17th, 2014|News, Press, Rightbox|Comments Off

FRAME’s new Director

FRAME has appointed a new Director to oversee its research programme at the Nottingham office. Dr Gerry Kenna is a drug safety scientist with extensive industrial safety assessment experience, including 11 years in the pharmaceutical industry. Prior to that he had a highly successful academic career. He is recognised nationally and internationally in the field […]

October 6th, 2014|Press, Rightbox|Comments Off