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ATLA - ISI
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Alternatives to Laboratory Animals - ATLA

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ATLA Volume 35, No 1

March 2007

 

Robert Combes
Editorial: Reproductive Toxicity Testing under the REACH System — Time for a Paradigm Shift    [ PDF ]


News & Views  [ Abstract ]   [ PDF ]


ECVAM News & Views  [ Abstract ]   [ PDF ]


Second Joint Conference of the Estonian Society of Toxicology and the Scandinavian Society for Cell Toxicology  [ Abstract ]   [ PDF ]

Iiris Kahn, Uko Maran, Emilio Benfenati, Tatiana I. Netzeva, T. Wayne Schultz and Mark T.D. Cronin
Comparative Quantitative Structure–Activity–Activity Relationships for Toxicity to Tetrahymena pyriformis and Pimephales promelas  [ Abstract ]   [ PDF ]

Daniel C. Neagu, Gongde Guo, Paul R. Trundle and Mark T.D. Cronin
A Comparative Study of Machine Learning Algorithms Applied to Predictive Toxicology Data Mining  [ Abstract ]   [ PDF ]

Cecilia Clemedson, Ada Kolman and Anna Forsby
The Integrated Acute Systemic Toxicity Project (ACuteTox) for the Optimisation and Validation of Alternative In Vitro Tests  [ Abstract ]   [ PDF ]

Michael Gülden and Hasso Seibert
The Improvement of In Vitro Cytotoxicity Testing for the Assessment of Acute Toxicity in Fish  [ Abstract ]   [ PDF ]

Zuzana Kovácviková, Erzsébet Tátrai, Elena Piecková Jana Tulinská, Zuzana Pivovarová, Mirjana Mataušic-Pišl, Miroslava Kuricová and Ladislava Wsolová
An In Vitro Study of the Toxic Effects of Stachybotrys chartarum Metabolites on Lung Cells  [ Abstract ]   [ PDF ]

Daiva Baltriukiene, Audrone Kalvelyte and Virginija Bukelskiene
Induction of Apoptosis and Activation of JNK and p38 MAPK Pathways in Deoxynivalenol-Treated Cell Lines  [ Abstract ]   [ PDF ]

Jens Noraberg, Carsten V. Jensen, Christian Bonde, Maria Montero, Jakob V. Nielsen, Niels A. Jensen and Jens Zimmer
The Developmental Expression of Fluorescent Proteins in Organotypic Hippocampal Slice Cultures from Transgenic Mice and its Use in the Determination of Excitotoxic Neurodegeneration  [ Abstract ]   [ PDF ]

Alzbeta Mlynarcíková, Mária Ficková and Sona Scsuková
The Effects of Selected Phenol and Phthalate Derivatives on Steroid Hormone Production by Cultured Porcine Granulosa Cells  [ Abstract ]   [ PDF ]

Petr Mlejnek, Ivo Frydrych and Petr Dolez∨el
Cyclosporin A Potentiates the Cytotoxic Effects of Methyl Methanesulphonate in HL-60 and K562 Cells  [ Abstract ]   [ PDF ]

Malgorzata Witeska and Marta Wakulska
The Effects of Heavy Metals on Common Carp White Blood Cells In Vitro  [ Abstract ]   [ PDF ]

Virginija Kalciene and Anolda C∨etkauskaite
Environmental and Synthetic Sulphydryl Group Inhibitors: Effects on Bioluminescence and Respiration in Vibrio fischeri  [ Abstract ]   [ PDF ]

Margit Heinlaan, Anne Kahru, Kaja Kasemets, Imbi Kurvet, Cristophe Waterlot, Kalev Sepp, Henri-Charles Dubourguier and Francis Douay
Rapid Screening for Soil Ecotoxicity with a Battery of Luminescent Bacteria Tests  [ Abstract ]   [ PDF ]

Natalya Irha and Irina Blinova
The Use of Bioassays for the Risk Assessment of Toxic Leachates: An Experimental Study  [ Abstract ]   [ PDF ]

Uuve Kirso, Natalya Irha, Janek Reinik, Gary Urb and Margit Laja
The Role of Laboratory and Field Leaching Tests in Hazard Identification for Solid Materials  [ Abstract ]   [ PDF ]

Anatoly S. Loukianov, Tatiana K. Syomina and Aleksander M. Korolev
Conformational Changes in Proteins In Vitro as a Means of Predicting the Acute Toxicities of Chemicals  [ Abstract ]   [ PDF ]

David Basketter, Camilla Pease, Gerald Kasting, Ian Kimber, Silvia Casati, Mark Cronin, Walter Diembeck, Frank Gerberick, Jonathan Hadgraft, Thomas Hartung, Jean Paul Marty, Efstathios Nikolaidis, Grace Patlewicz, David Roberts, Erwin Roggen, Costanza Rovida and Johannes van de Sandt
Skin Sensitisation and Epidermal Disposition: The Relevance of Epidermal Disposition for Sensitisation Hazard Identification and Risk Assessment: The Report and Recommendations of ECVAM Workshop 59  [ Abstract ]   [ PDF ]

Robert Combes and Michael Balls
Comment: Comments on the Sub-group Reports of the EU Technical Expert Working Group on the Revision of Directive 86/609/EEC on the Protection of Animals Used for Experimental and Other Scientific Purposes  [ Abstract ]   [ PDF ]

Michelle Hudson
Comment: Why do the Numbers of Laboratory Animal Procedures Conducted Continue to Rise? An Analysis of the Home Office Statistics of Scientific Procedures on Living Animals: Great Britain 2005  [ Abstract ]   [ PDF ]