Andrew N. Rowan
Fourth World Congress - Preface  [ Abstract ]   [ PDF ]

Fourth World Congress - Contents    [ PDF ]

W.M.S. Russell
Fourth World Congress - Special contribution: Nine Glorious Years    [ PDF ]

Paul De Greeve, Wim De Leeuw and Bert F.M. van Zutphen
Plenary lecture: Trends in Animal Use and Animal Alternatives  [ Abstract ]   [ PDF ]

Jean S. Fleming
Plenary lecture - Ethical, Cultural and Spiritual Objections to Genetically Modified Organisms: A Review of the New Zealand Process and Perspective  [ Abstract ]   [ PDF ]

Adrian J. Smith and Karina Smith
Plenary lecture - Guidelines for Humane Education: Alternatives to the Use of Animals in Teaching and Training  [ Abstract ]   [ PDF ]

Robert D. Combes
The Use of Human Cells in Biomedical Research and Testing  [ Abstract ]   [ PDF ]

Samantha Orr and Jacki Trafford
The Establishment of the UK Human Tissue Bank  [ Abstract ]   [ PDF ]

Peggy Papeleu, Pascal Loyer, Tamara Vanhaecke, Tom Henkens, Greetje Elaut, Christiane Guguen-Guillouzo and Vera Rogiers
Proliferation of Epidermal Growth Factor-stimulated Hepatocytes in a Hormonally Defined Serum-free Medium  [ Abstract ]   [ PDF ]

Celia P. Martínez-Jiménez, Ramiro Jover, Maria José Gómez-Lechón and José V. Castell
Can Hepatoma Cell Lines be Redifferentiated to be Used in Drug Metabolism Studies?  [ Abstract ]   [ PDF ]

Joseph Kubilus, Patrick J. Hayden, Seyoum Ayehunie, Sarah D.K. Lamore, Cynthia Servattalab, Kristen L. Bellavance, John E. Sheasgreen and Mitchell Klausner
Full Thickness EpiDerm™: a Dermal–Epidermal Skin Model to Study Epithelial–Mesenchymal Interactions  [ Abstract ]   [ PDF ]

Roland Roguet
The Use of Reconstructed Human Epidermis EPISKIN™ in the Assessment of Local Tolerance of Cosmetics and Chemicals  [ Abstract ]   [ PDF ]

Marlies Halder, Michael Balls, Coenraad Hendriksen and Klaus Cussler
ECVAM’s Activities in Promoting the Three Rs in the Quality Control of Biologicals  [ Abstract ]   [ PDF ]

Yasuyuki Sakai, Osamu Fukuda, Sue-Hyung Choi and Akiyoshi Sakoda
Use of a Perfusion Co-culture System Consisting of Caco-2 and Hep G2 Cell Compartments for the Kinetic Analysis of Benzo[a]pyrene Toxicity  [ Abstract ]   [ PDF ]

Greetje Elaut, Gabriëlla Török, Peggy Papeleu, Tamara Vanhaecke, Georges Laus, Dirk Tourwé and Vera Rogiers
Rat Hepatocyte Suspensions as a Suitable In Vitro Model for Studying the Biotransformation of Histone Deacetylase Inhibitors  [ Abstract ]   [ PDF ]

Nicolas Fabre, Elsa Arrivet, Françoise Paillard, Valérie Wibaut-Berlaimont, Nicole Bichet, Nigel O. Roome, Annick Prenez and Joan-Albert Vericat
A New Human Hepatoma Cell Line to Study Repeated Cell Toxicity  [ Abstract ]   [ PDF ]

Vera Baumans
Report of the Workshop on Fetal Bovine Serum Replacement in Cell Cultures    [ PDF ]

John McArdle
Report of the Workshop on Monoclonal Antibodies    [ PDF ]

André Schratten
Potential of Comprehensive Toxico-proteomics: Quantitative and Differential Mining of Functional Proteomes from Native Samples  [ Abstract ]   [ PDF ]

Michael F.W. Festing
Good Experimental Design and Statistics Can Save Animals, But How Can it Be Promoted?  [ Abstract ]   [ PDF ]

Rajendra S. Chhabra, Nancy B. Ress, John W. Harbell and Rodger D. Curren
Evaluation of Some In Vitro Tests to Reduce and Replace the Sub-acute Animal Toxicity Studies  [ Abstract ]   [ PDF ]

David J. Mellor
Taming and Training of Pregnant Sheep and Goats and of Newborn Lambs, Kids and Calves before Experimentation  [ Abstract ]   [ PDF ]

David J. Mellor and Vera Baumans
Introduction: Evaluation Techniques for Animal Well-being    [ PDF ]

Sarah Wolfensohn
Social Housing of Large Primates: Methodology for Refinement of Husbandry and Management  [ Abstract ]   [ PDF ]

Georgia Mason, David Wilson, Charlotte Hampton and Hanno Würbel
Non-invasively Assessing Disturbance and Stress in Laboratory Rats by Scoring Chromodacryorrhoea  [ Abstract ]   [ PDF ]

Vera Baumans
Methods for Evaluation of Laboratory Animal Well-being  [ Abstract ]   [ PDF ]

Eva Waiblinger and Barbara König
Refinement of Gerbil Housing and Husbandry in the Laboratory  [ Abstract ]   [ PDF ]

Rosemarie Einstein, Robyn L. Billing, Anureet Singh and Irene Chin
Implanted Telemetry Transmitters Alter the Noradrenergic Response in Vas Deferens from Mice  [ Abstract ]   [ PDF ]

Klaas Kramer, Heleen van de Weerd, Anne Mulder, Caroline Van Heijningen, Vera Baumans, René Remie, Hans-Peter Voss and Bert F.M. van Zutphen
Effect of Conditioning on the Increase of Heart Rate and Body Temperature Provoked by Handling in the Mouse  [ Abstract ]   [ PDF ]

David Anderson
Revision of Council of Europe Convention ETS 123 Guidelines for the Accommodation and Care of Animals Used for Experimental and Other Scientific Purposes  [ Abstract ]   [ PDF ]

Ursula G. Sauer
The Revision of European Housing Guidelines for Laboratory Animals: Expectations from the Point of View of Animal Welfare  [ Abstract ]   [ PDF ]

Kay L. Stewart
The Environmental Enrichment Committee  [ Abstract ]   [ PDF ]

Ajit Kale1 Ivo Amende, Katrina Piskorski, Victor Chu, Jose M. Otero, Peter Mueller and Thomas G. Hampton
Non-invasive Physiology in Conscious Mice  [ Abstract ]   [ PDF ]

Christian Cook and David Thomas
Reducing the Invasiveness of Obtaining Blood-borne Measures in Animals  [ Abstract ]   [ PDF ]

James K. Kirkwood
Use and Pitfalls of Allometry: A Valuable Tool in Comparisons and Extrapolations Between Species and in Ethical Considerations Concerning the Use of One Species to Model Another  [ Abstract ]   [ PDF ]

Gilly Griffin and Clément Gauthier
Incorporation of the Principles of the Three Rs in Wildlife Research  [ Abstract ]   [ PDF ]

Jane Conole
The Ethics of Research on Companion Animals for the Benefit of Their Own Species  [ Abstract ]   [ PDF ]

Michael D. Rickard
The Use of Animals for Research on Animal Diseases: Its Impact on the Harm–Benefit Analysis  [ Abstract ]   [ PDF ]

Bruce Warburton and Cheryl O’Connor
Research on Vertebrate Pesticides and Traps: Do Wild Animals Benefit?  [ Abstract ]   [ PDF ]

Ian G. Colditz
Welfare Benefits to Farm Animals from Their Use in Research  [ Abstract ]   [ PDF ]

Derek Fry
Reduction by Well-defined Objectives  [ Abstract ]   [ PDF ]

Sylvia Vaughan
Optimising Resources by Reduction: The FRAME Reduction Committee  [ Abstract ]   [ PDF ]

Maria Puopolo, Aldina Venerosi Pesciolini, Flavia Chiarotti and Laura Ricceri
Adequate Statistical Methods to Reduce the Number of Animals Used in Behavioural Experiments: The Analysis of the Behavioural Transitions  [ Abstract ]   [ PDF ]

Michael F.W. Festing
Refinement and Reduction Through the Control of Variation  [ Abstract ]   [ PDF ]

Paul Flecknell and Alicia Karas
Assessing and Managing Pain and Distress for Ethics Committees    [ PDF ]

David J. Mellor and Kevin J. Stafford
Physiological and Behavioural Assessment of Pain in Ruminants: Principles and Caveats  [ Abstract ]   [ PDF ]

Clément Gauthier
Overview and Analysis of Animal Use in North America  [ Abstract ]   [ PDF ]

A.C. David Bayvel
Animal Use Statistics: The New Zealand and Australian Experience and Perspective  [ Abstract ]   [ PDF ]

Jon D. Richmond
Animal Use in the United Kingdom in 2001  [ Abstract ]   [ PDF ]

Yukihisa Matsuda
Recent Trends in the Number of Laboratory Animals Used in Japan  [ Abstract ]   [ PDF ]

Annamaria Passantino, Marzio Panichi, Maria Rachele Russo and Michele Passantino
Ethics for Research Using Animals in Italy  [ Abstract ]   [ PDF ]

David B. Morton
The Welfare of Non-human Primates in Research in the EU  [ Abstract ]   [ PDF ]

Ursula G. Sauer
The Moral Standing of Non-human Primates: Why They Merit Special Consideration  [ Abstract ]   [ PDF ]

Kathleen M. Conlee, Erika H. Hoffeld and Martin L. Stephens
A Demographic Analysis of Primate Research in the United States  [ Abstract ]   [ PDF ]

Mark J. Prescott and Maggy Jennings
Ethical and Welfare Implications of the Acquisition and Transport of Non-human Primates for Use in Research and Testing  [ Abstract ]   [ PDF ]

Neil Wells
The Great Ape Project: Legislating for the Control of the Use of Non-human Hominids in Research, Testing and Teaching — Animal Welfare Act 1999 (New Zealand)  [ Abstract ]   [ PDF ]

Andrew Nicholson, Jessica Sandler and Troy Seidle
An Evaluation of the US High Production Volume (HPV) Chemical-testing Programme: A Study in (Ir)Relevance, Redundancy and Retro Thinking  [ Abstract ]   [ PDF ]

Ursula G. Sauer
The New EU Chemicals Policy: Challenges and Chances for Animal-free Test Methods  [ Abstract ]   [ PDF ]

Vera Rogiers
ECOPA: The European Consensus Platform on Three Rs Alternatives  [ Abstract ]   [ PDF ]

Jon D. Richmond
Humane Regulatory Testing: The United Kingdom Experience  [ Abstract ]   [ PDF ]

Sidney Green and Alan M. Goldberg
TestSmart and Toxic Ignorance  [ Abstract ]   [ PDF ]

Irmela W. Ruhdel
EU Sales Ban on New Cosmetics Tested on Animals: Impact on Alternative Methods, WTO Implications and Animal Welfare Aspects  [ Abstract ]   [ PDF ]

Vicky Robinson and Maggy Jennings
Refinement and Reduction in the Production of Genetically Modified Mice: Sixth Report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement  [ Abstract ]   [ PDF ]

A.C. David Bayvel
Animal Use in Biotechnology: Issues and Options — A New Zealand Perspective  [ Abstract ]   [ PDF ]

Lino Enrique Paula
Effective Policies in the Animal Genomics Era: How Best to Involve Ethics, Expertise and the Public  [ Abstract ]   [ PDF ]

Miranda Gott and Vaughan Monamy
Ethics and Transgenesis: Toward a Policy Framework Incorporating Intrinsic Objections and Societal Perceptions  [ Abstract ]   [ PDF ]