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Alternatives to Laboratory Animals - ATLA

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ATLA Volume 29, No 3

May 2001


Nancy Rothwell
Editorial: Scientific Progress and Animal Welfare: Conflicting Goals or Complementary Opportunities?    [ PDF ]

News & Views  [ Abstract ]   [ PDF ]

Cecilia Clemedson
The Eighteenth Workshop of the Scandinavian Society for Cell Toxicology  [ Abstract ]   [ PDF ]

Paul J. Dierickx, Claudia Smit and Ellen M. Scheers
Cytotoxicity of the MEIC Reference Chemicals in Antioxidant-enriched Rat Hepatoma-derived Fa32 cells  [ Abstract ]   [ PDF ]

Maria J. Gómez-Lechón, Xavier Ponsoda, Roque Bort and José V. Castell
The Use of Cultured Hepatocytes to Investigate the Metabolism of Drugs and Mechanisms of Drug Hepatotoxicity  [ Abstract ]   [ PDF ]

Thomas Helleday, Fredrik Johansson and Dag Jenssen
The DRAG Test: an Assay for Detection of Genotoxic Damage  [ Abstract ]   [ PDF ]

Petr Mlejnek
Caspase-3 Activity and Carbonyl Cyanide m-Chlorophenylhydrazone-induced Apoptosis in HL-60 cells  [ Abstract ]   [ PDF ]

Helmut Segner and Jean-Pierre Cravedi
Metabolic Activity in Primary Cultures of Fish Hepatocytes  [ Abstract ]   [ PDF ]

Lee Põllumaa, Alla Maloveryan, Marina Trapido, Helgi Sillak and Anne Kahru
Study of the Environmental Hazard Caused by the Oil Shale Industry Solid Waste  [ Abstract ]   [ PDF ]

Herman Sahlin and Håkan Nygren
Cytotoxicity Testing of Wound-Dressing Materials  [ Abstract ]   [ PDF ]

Pirjo Lindström-Seppä, Katalin Urban, Ulla Honkalampi- Hämäläinen and Sashwati Roy
Biochemical Responses in Aquatic Plants as Markers of Environmental Contamination  [ Abstract ]   [ PDF ]

Frode Fonnum, Oddvar Myhre, Øyvind A. Voie, Jannike M. Andersen and Anne Dreiem
The Formation of Free Radicals in Human Granulocytes and Cerebellar Granule Cells  [ Abstract ]   [ PDF ]

Ina Schuppe-Koistinen
Molecular Profiling and Prediction of Toxicity  [ Abstract ]   [ PDF ]

Mattias Öberg, Patrik L. Andersson, Niklas Johansson, Mats Tysklind and Helen Håkansson
Multivariate Modelling of Polychlorinated Biphenyl-induced CYP1A Activity in the MH1C1 Rat Hepatoma Cell Line  [ Abstract ]   [ PDF ]

Ellen. M. Scheers, Barbro Ekwall and Paul J. Dierickx
Long-term In Vitro Toxicity of 27 MEIC Chemicals on Hep G2 Cells  [ Abstract ]   [ PDF ]

Horst Spielmann, Elke Genschow, Gabriele Scholz, Nigel A. Brown, Aldert H. Piersma, Madeleine Brady, Nicole Clemann, Hannele Huuskonen, Francoise Paillard, Susanne Bremer and Klaus Becker
Preliminary Results of the ECVAM Validation Study on Three In Vitro Embryotoxicity Tests  [ Abstract ]   [ PDF ]

Magnus Ingelman-Sundberg
Integration of In Vitro Approaches to Predict Drug Metabolism and Interaction in Man: An EU Validation Project  [ Abstract ]   [ PDF ]

Erik Walum
Test Validation: From Animal Data Comparison to Prospective Evaluation  [ Abstract ]   [ PDF ]

Apolonia Novillo, Barbro Ekwall and Argelia Castaño
Protein Precipitation In Vitro as a Measure of Chemical-induced Cytotoxicity: an EDIT Sub-programme  [ Abstract ]   [ PDF ]

Jesper J. Hedberg, Annette Hansson, Jan A. Nilsson, Jan-Olov Höög and Roland C. Grafström
Uniform Expression of Alcohol Dehydrogenase 3 in Epithelia Regenerated with Cultured Normal, Immortalised and Malignant Human Oral Keratinocytes  [ Abstract ]   [ PDF ]

Tamara Vanhaecke, André Foriers, Albert Geerts, Elizabeth A. Shephard, Antoine Vercruysse and Vera Rogiers
Pyruvate-induced Long-term Maintenance of Glutathione S-Transferase in Rat Hepatocyte Cultures  [ Abstract ]   [ PDF ]

Heike Pospisil and Hermann-Georg Holzhütter
A Compartment Model to Calculate Timedependent Concentration Profiles of Topically Applied Chemical Compounds in the Anterior Compartments of the Rabbit Eye  [ Abstract ]   [ PDF ]

Donald W. Straughan
Comment: A Major Initiative from the European Pharmaceutical Industry and ECVAM  [ Abstract ]   [ PDF ]

Book Reviews  [ Abstract ]   [ PDF ]