Robert Combes
Editorial: The EU White Paper: Strategy for a Future Chemicals Policy (an Idea that Must Have Seemed Good at the Time!)    [ PDF ]

News & Views  [ Abstract ]   [ PDF ]

Derek J. Knight and Damien Breheny
Alternatives to Animal Testing in the Safety Evaluation of Products  [ Abstract ]   [ PDF ]

Mariangela Prati, Rosalba Gornati, Patrizia Boracchi, Elia Biganzoli, Salvador Fortaner, Romano Pietra, Enrico Sabbioni and Giovanni Bernardini
A Comparative Study of the Toxicity of Mercury Dichloride and Methylmercury, Assayed by the Frog Embryo Teratogenesis Assay–Xenopus (FETAX)  [ Abstract ]   [ PDF ]

Ayako Sakai, Yumiko Iwase, Yoshiyuki Nakamura, Kiyoshi Sasaki, Noriho Tanaka and Makoto Umeda
Use of a Cell Transformation Assay with Established Cell Lines, and a Metabolic Cooperation Assay with V79 Cells for the Detection of Tumour Promoters: A Review  [ Abstract ]   [ PDF ]

Paul J. Dierickx, Jacques O. De Beer and Ellen M. Scheers
Cystathionine Pathway-dependent Cytotoxicities of Diethyl Maleate and Diamide in Rat and Human Hepatoma-derived Cell Cultures  [ Abstract ]   [ PDF ]

Annalaura Stammati, Rosario Nicoletti, Salvatore De Stefano, Franco Zampaglioni & Flavia Zucco
Cytostatic Properties of a Novel Compound Derived from Penicillium pinophilum: An In Vitro Study  [ Abstract ]   [ PDF ]

Susanne Bremer, Cristian Pellizzer, Sandra Coecke, Martin Paparella and Paolo Catalani
Detection of the Embryotoxic Potential of Cyclophosphamide by Using a Combined System of Metabolic Competent Cells and Embryonic Stem Cells  [ Abstract ]   [ PDF ]

Daniel Arrieta Baez, Gerardo Zepeda Vallejo, Patricia Cano Sánchez, Matilde Breña Valle, Ricardo Reyes Chilpa and Manuel Jiménez Estrada
Use of the SOS-chromotest Spot Assay as a Screening System for Detecting Genotoxic Compounds in Crude Plant Extracts  [ Abstract ]   [ PDF ]

Marlies Halder, Coenraad Hendriksen, Klaus Cussler and Michael Balls
ECVAM's Contributions to the Implementation of the Three Rs in the Production and Quality Control of Biologicals  [ Abstract ]   [ PDF ]

Valérie Zuang, Michael Balls, Philip A. Botham, Alain Coquette, Emanuela Corsini, Rodger D. Curren, Graham R. Elliott, Julia H. Fentem, Jon R. Heylings, Manfred Liebsch, Jesús Medina, Roland Roguet, Johannes J.M. van de Sandt, Christianne Wiemann and Andrew P. Worth
Follow-up to the ECVAM Prevalidation Study on In Vitro Tests for Acute Skin Irritation ECVAM Skin Irritation Task Force Report 2  [ Abstract ]   [ PDF ]

Elizabeth S. Jenkins and Robert D. Combes
Comment: A Critique of the Animal Procedures Committee Report on Biotechnolog  [ Abstract ]   [ PDF ]