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Alternatives to Laboratory Animals - ATLA

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ATLA Volume 31, S1

June 2003


Michael Balls
Introduction    [ PDF ]

Lutz Edler and Carina Ittrich
Biostatistical Methods for the Validation of Alternative Methods for In Vitro Toxicity Testing  [ Abstract ]   [ PDF ]

Ludwig A. Hothorn
Statistics of Interlaboratory In Vitro Toxicological Studies  [ Abstract ]   [ PDF ]

Dieter Hauschke, Torsten Hothorn and Juliane Schäfer
The Role of Control Groups in Mutagenicity Studies: Matching Biological and Statistical Relevance  [ Abstract ]   [ PDF ]

Dieter Hauschke and Ludwig A. Hothorn
Two-stage Testing of Safety: A Statistical View  [ Abstract ]   [ PDF ]

Frank Bretz and Ludwig A. Hothorn
Statistical Analysis of Monotone or Non-monotone Dose–Response Data from In Vitro Toxicological Assays  [ Abstract ]   [ PDF ]

Ludwig A. Hothorn and Frank Bretz
Dose–Response and Thresholds in Mutagenicity Studies: A Statistical Testing Approach  [ Abstract ]   [ PDF ]