Michael Balls
Editorial: Replacing, Reducing and Refining Animal Experiments: Making Sound Progress, but Must do Better    [ PDF ]

News & Viewes  [ Abstract ]   [ PDF ]

IIVS News & Views  [ Abstract ]   [ PDF ]

Michael Balls
Preface: Special Anniversary Volume - Issue 6: Replacement - Focus on the Testing of Chemicals and Products  [ Abstract ]   [ PDF ]

Paul Carmichael, Michael Davies, Matt Dent, Julia Fentem, Samantha Fletcher, Nicola Gilmour, Cameron MacKay, Gavin Maxwell, Leona Merolla, Camilla Pease, Fiona Reynolds and Carl Westmoreland
Non-Animal Approaches for Consumer Safety Risk Assessments: Unilever’s Scientific Research Programme  [ Abstract ]   [ PDF ]

John Sheasgreen, Mitch Klausner, Helena Kandárová and David Ingalls
The MatTek Story — How the Three Rs Principles Led to 3-D Tissue Success!  [ Abstract ]   [ PDF ]

Rodger Curren
Animal Use in the Chemical and Product Manufacturing Sectors — Can the Downtrend Continue?  [ Abstract ]   [ PDF ]

Michael Balls and Richard Clothier
FRAME and the Validation Process  [ Abstract ]   [ PDF ]

Horst Spielmann
The Way Forward in Reproductive/Developmental Toxicity Testing  [ Abstract ]   [ PDF ]

Natalia Y. Cockcroft, Oluwatobiloba Oke, Fiona Cunningham, Emma Bishop, Ian M. Fearon, Roman Zantl and Marianna D. Gaça
An In Vitro Perfusion System to Examine the Responses of Endothelial Cells to Simulated Flow and Inflammatory Stimulation  [ Abstract ]   [ PDF ]

Helena Kandárová, Patrick Hayden, Mitch Klausner, Joseph Kubilus, Paul Kearney and John Sheasgreen
In Vitro Skin Irritation Testing: Improving the Sensitivity of the EpiDerm Skin Irritation Test Protocol  [ Abstract ]   [ PDF ]