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ATLA - ISI
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Alternatives to Laboratory Animals - ATLA

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ATLA Volume 37, S1

September 2009

 

Margaret Clotworthy and Kathy Archibald
Introduction to the Proceedings of the Speed and Safety in Drug Discovery Symposium, hosted by the Safer Medicines Trust  [ Abstract ]   [ PDF ]

Robert A. Coleman
Drug Discovery and Development Tomorrow — Changing the Mindset  [ Abstract ]   [ PDF ]

Chris Hillier and David Bunton
Could Fresh Human Tissues Play a Key Role in Drug Development?  [ Abstract ]   [ PDF ]

Gregory T. Baxter
Hurel™ — an In Vivo-surrogate Assay Platform for Cellbased Studies  [ Abstract ]   [ PDF ]

Russell G. Higbee, Anthony M. Byers, Vipra Dhir, Donald Drake, Heather G. Fahlenkamp, Jyoti Gangur, Anatoly Kachurin, Olga Kachurina, Del Leistritz, Yifan Ma, Riyaz Mehta, Eric Mishkin, Janice Moser, Luis Mosquera, Mike Nguyen, Robert Parkhill, Santosh Pawar, Louis Poisson, Guzman Sanchez-Schmitz, Brian Schanen, Inderpal Singh, Haifeng Song, Tenekua Tapia, William Warren and Vaughan Wittman
An Immunologic Model for Rapid Vaccine Assessment — A Clinical Trial in a Test Tube  [ Abstract ]   [ PDF ]

Johannes Doehmer
The Use and Value of In Vitro Technologies in Metabolism Studies  [ Abstract ]   [ PDF ]

Quin Wills and Cathrine Mitchell
Toxicogenomics in Drug Discovery and Development — Making an Impact  [ Abstract ]   [ PDF ]

Marina Kleiman, Yael Sagi, Naamah Bloch and Zvia Agur
Use of Virtual Patient Populations for Rescuing Discontinued Drug Candidates and for Reducing the Number of Patients in Clinical Trials  [ Abstract ]   [ PDF ]

Katya Tsaioun and Mary Jacewicz
De-Risking Drug Discovery with ADDME — Avoiding Drug Development Mistakes Early  [ Abstract ]   [ PDF ]

Markus Müller
Monitoring Tissue Drug Levels by Clinical Microdialysis  [ Abstract ]   [ PDF ]

Mark Seymour
The Best Model for Humans is Human — How to Accelerate Early Drug Development Safely  [ Abstract ]   [ PDF ]