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ATLA - ISI
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Alternatives to Laboratory Animals - ATLA

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Chapter 6: Local Toxicity: Sensitisation



Skin and respiratory sensitisation are considered separately from acute dermal and ocular toxicity, since they are effects that may arise following an initial exposure to a sensitiser (by any route of exposure, and possibly via the systemic circulation), when a susceptible individual is subsequently exposed by way of the dermal or inhalation routes.