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Alternatives to Laboratory Animals - ATLA

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Multivariate Modelling of Polychlorinated Biphenyl-induced CYP1A Activity in the MH1C1 Rat Hepatoma Cell Line

Mattias Öberg, Patrik L. Andersson, Niklas Johansson, Mats Tysklind and Helen Håkansson

The large number of chemicals in the environment, and possible interactions between these substances, constitute two of the major problems of contemporary risk assessment. We aim to meet these problems with a strategy that combines the use of multivariate statistics and in vitro techniques