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The Assessment of Repeated Dose Toxicity In Vitro: A Proposed Approach The Report and Recommendations of ECVAM Workshop 56

Pilar Prieto,Alan W. Baird,Bas J. Blaauboer,Jose Vicente Castell Ripoll,Raffaella Corvi, Wolfgang Dekant,Paul Dietl,Alessandra Gennari,Laura Gribaldo, Julian L. Griffin, Thomas Hartung, Jerry J. Heindel,Peter Hoet, Paul Jennings,Luciana Marocchio,Jens Noraberg,Patricia Pazos,Carl Westmoreland,Armin Wolf,Jayne Wright and Walter Pfaller

This is the 56th report of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). The ECVAM workshop on repeated dose toxicity in vitro was held on 15–17 September 2004, at ECVAM in Ispra, Italy. The workshop was chaired by Walter Pfaller and Pilar Prieto, and was attended by pharmacologists and toxicologists from academia, industry and government, from different research backgrounds and with different ways of thinking. The main goal was to discuss and evaluate alternative approaches to in vivo repeated dose toxicity testing.