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Alternatives to Laboratory Animals - ATLA

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A Review of the Implementation of the Embryonic Stem Cell Test (EST) - The report and recommendations of an ECVAM/ReProTect Workshop

Philip Marx-Stoelting, Els Adriaens, Hans-Jürgen Ahr, Susanne Bremer, Bernward Garthoff, Heinz-Peter Gelbke, Aldert Piersma, Cristian Pellizzer,4Ulrike Reuter, Vera Rogiers, Barbara Schenk, Silke Schwengberg, Andrea Seiler, Horst Spielmann, Margino Steemans, Donald B. Stedman, Philippe Vanparys, Joan Albert Vericat, Miriam Verwei, Femke van de Water, Marc Weimer and Michael Schwarz

The new European chemicals policy for the Registration, Evaluation, Authorisation and Restriction of Chemicals (the REACH system), requires the routine toxicological testing of chemicals produced in volumes of more than one tonne per year, in order to enhance environmental and consumer safety (1). Under the REACH system policy, it will be most probably necessary to test several thousand chemicals for their toxicological properties.

Full text pdf 37(3) 313–328