1978 was an important year for understanding the frequency and application of animals used in experiments in Great Britain.  It was the first year in which the Home Office made public the national statistics regarding things such as the species used, the primary purpose of the study, use of anaesthesia, and licensing, amongst others.  The in-depth report highlighted the areas of animal experimentation that are of concern, while providing insight into other areas that may be overlooked.  The report has been published annually since 1978, and is a primary resource for those interested in how and where animals are being used in scientific procedures.  With almost 40 years’ worth of data it is possible to plot the trends in use to determine if certain species or procedures have increased or decreased over time, and is a very good indicator where alternatives research should focus.