• Cynomolgus monkey

New research casts doubt on monkeys as drug testing model

FRAME is calling for increased investment in cell-based and computer methods of drug testing following new research that demonstrates serious flaws in an animal model.

Cynomolgus monkeys are considered a valuable species for drug testing because of their size and their relatively close genetic parallels with humans. Now new experiments […]

  • Monkey

Cynomolgus monkeys and paracetamol: background paper

Cynomolgus monkeys are resistant to drug induced liver injury caused by paracetamol
by Dr Gerry Kenna
FRAME  Scientific Director

Prior to their registration for use in humans, all new drugs are subjected to a large battery of safety […]


 FRAME’s Timeline is a useful source of information on key points in the development of alternatives to animal methods. Visit the Timeline
ATLA – Alternatives to Laboratory Animals – is FRAME’s peer-reviewed scientific journal, published six times a year. Visit the website
PiLAS – Perspectives in Laboratory Animal Science – is a place for bioscientists to discuss aspects of lab animal use. Visit the website
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What FRAME does

There is no worldwide agreement that protects the welfare of animals either in the wild or those involved in research and testing. While EU law says that alternative methods should be used if they are available, there are many areas where no effective non-animal methods exist. The latest Directive says EU member states should support alternatives, but there is no specific legal requirement to create them. FRAME is helping to find them.

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FRAME was the first organisation to fund its own laboratory to research new and innovative ways to replace animals in medical and scientific experiments. Many of the non-animal tests it developed are now in common use.Read more...
 
FRAME issues regular press releases and statements to the media. It has appeared in local and national newspapers and on TV and radio. Read more...